SNP genotyping
Our flexible and cost effective SNP and InDel genotyping service, utilises the proprietary KASP genotyping
reagent system combined with the SNPline instrumentation.
Our unique approach to assay miniaturisation
and 1536 PCR format enables unrivalled flexibility and the generation of data sets from 1 SNP over as few as
20 samples to thousands of SNP's over thousands of samples. |
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DNA sequencing
Our dedicated sequencing teams use state-of-the-art technologies to provide customers with a fast, personalised
service, to generate the highest quality data and value for money.
We offer both traditional Sanger and next
generation technologies: |
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Nucleic acid preparation
Our high quality DNA and RNA extraction services utilise both well-proven technologies (commerically available
and based on our own IP) to deliver a professional, customised extraction service. Project needs are met by
preparing samples from virtually any starting material.
The service portfolio includes:
| • DNA extraction – blood, saliva, buccal swabs, tissue,
plant material, forensic samples and cell cultures |
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• DNA normalisation |
• RNA extraction – blood, tissue, bacterial and cell
cultures |
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• Vigorous QC checks – Barcoding, quantification,
confirmatory SNP genotyping |
| • Oragene® DNA sample collection tubes |
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• Long-term storage of customer samples |
• WGA
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• Generation of multi-site backup stocks. |
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Reagents and consumables
The same reagents we use for delivery of our high-quality, cost-effective laboratory
services are available for use in our customer's laboratories worldwide.
KASP assays
The proprietary KASP assays for detection of SNPs and InDels is available in two formats
using our On Demand service for a fully validated and optimised set of primers and
the By Design service in which primers are developed and optimised in silico prior to shipment.
KASPar mastermix
The KASPar mastermix contains our unique KlearTaq Hot-start Taq polymerase
combined with optimised reaction buffer and dNTPs required for genotyping using
our KASP assays. We also offer a range of mastermix solutions (KlearKall) which
can be employed to reduce costs with existing chemistries including Taqman®.
KlearTaq and KlearTaq Hifi
Our KlearTaq and KlearTaq Hifi Hot-start Taq polymerases provide highly flexible,
robust and efficient enzymes for use in PCR applications.
Nucleic acid extraction
As with our other reagent systems, there are a range of kit options to deliver a format
suitable for any throughput or extraction matrix:
• sbeadex®
• magTM
• KlearGene XL
• KlearGene spin plates. |